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Acceleration of Fracture Healing Modulated by Compounds That Stimulate Inducible Nitric Oxide Synthase

New approaches for bone healing in available literature are discussed. The first speaker briefly reviews six experiments on bone healing; these six papers include enhancement of healing modulated by components that stimulate inducible nitric oxide synthase, doxycycline-loaded coaxial nanofiber coating of titanium implants, three dimensional printed scaffolds for segmental defects in long bones, investigating an endothelial progenitor cell for the healing of critical size bone defects, surgery delays of fracture healing in a novel translational animal fracture model, and the assessment of reamer irrigator aspirator filtrate for its osteoinductive potential. The second speaker discusses the effects of nitric oxide in fracture healing in instances of neovascularity and osteoblastic differentiation.